Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) ABCG11 Polyclonal antibody

Uniprot No.

Q8RXN0

Target Names

ABCG11

Alternative Names

ABCG11; COF1; DSO; PEL1; WBC11; At1g17840; F2H15.7; ABC transporter G family member 11; ABC transporter ABCG.11; AtABCG11; Protein CUTICULAR DEFECT AND ORGAN FUSION 1; Protein DESPERADO; Protein PERMEABLE LEAVES 1; White-brown complex homolog protein 11; AtWBC11

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana ABCG11 protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Target Background

Function

Required for the cuticle, root suberin and pollen coat development by controlling cutin and maybe wax transport to the extracellular matrix. Involved in developmental plasticity and stress responses. Together with ABCG9 and ABCG14, required for vascular development by regulating lipid/sterol homeostasis. May be a transporter of lignin precursors during tracheary element differentiation.

Gene References into Functions

ABCG9, ABCG11 and ABCG14 are expressed in the vascular system. Mutations are responsible for defects in plant growth and affect vascular patterning. PMID: 24112720
ABCG11 and ABCG12 form a heterodimer. ABCG11 trafficking to the plasma membrane is independent of ABCG12. PMID: 20870961
The dso-4 phenotypes corresponded to the strong DSO/ABCG11 gene expression in the embryo epidermis as well as in the endosperm tissues of the developing seeds. Moreover, the DSO/ABCG11 protein displayed polar localization in the embryo protoderm. PMID: 20035035
results show that WBC11 (At1g17840) functions in secretion of surface waxes, possibly by interacting with CER5; however, unlike ABCG12/CER5, ABCG11/WBC11 is important to the normal process of cutin formation PMID: 17727615
findings show that DESPERADO (AtWBC11), encoding a plasma membrane-localized ATP-binding cassette transporter, is required for cutin transport to the extracellular matrix PMID: 17951461
wax and cutin monomers were both reduced in the atwbc11 mutant. AtWBC11 was widely expressed in aerial organs. Interestingly, we found that the expression was light dependent, and the phytohormone ABA up-regulated AtWBC11 expression PMID: 17989085

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Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Families

ABC transporter superfamily, ABCG family, Eye pigment precursor importer (TC 3.A.1.204) subfamily

Tissue Specificity

Expressed in seedlings, roots, stems, leaves, flowers, and siliques, mostly in epidermis, trichomes, vasculatures and developing tissues. Follows an uniparental maternal expression in the seed, thus being the product of a maternally expressed imprinted ge

Database Links

KEGG: ath:AT1G17840

STRING: 3702.AT1G17840.1

UniGene: At.41813

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ABCG11 Antibody

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