ACC1 Antibody

Code CSB-PA176534XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) ACC1 Polyclonal antibody
Uniprot No.
Target Names
ACC1
Alternative Names
ACC1 antibody; ABP2 antibody; FAS3 antibody; MTR7 antibody; YNR016C antibody; N3175Acetyl-CoA carboxylase antibody; ACC antibody; EC 6.4.1.2 antibody; Fatty acid synthetase 3 antibody; mRNA transport-defective protein 7) [Includes: Biotin carboxylase antibody; EC 6.3.4.14)] antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) ACC1 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Protein A/G
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nuclear envelope. Required for acylation and vacuolar membrane association of VAC8 which is necessary to maintain a normal morphology of the vacuole.
Gene References into Functions
  1. Data show that attenuated expression of acetyl-CoA carboxylase ACC1 results in increased acetylation of bulk histones, globally increased acetylation of chromatin histones, and altered transcriptional regulation. PMID: 22580297
Subcellular Location
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Database Links

KEGG: sce:YNR016C

STRING: 4932.YNR016C

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