ACBP2 Antibody

Code CSB-PA879837XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) ACBP2 Polyclonal antibody
Uniprot No.
Target Names
ACBP2
Alternative Names
ACBP2; At4g27780; T27E11.20; Acyl-CoA-binding domain-containing protein 2; Acyl-CoA binding protein 2
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana ACBP2 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Binds medium- and long-chain acyl-CoA esters with very high affinity. Can interact in vitro with palmitoyl-CoA, but not with oleoyl-CoA. Binds to lead ions (Pb). May function as an intracellular carrier of acyl-CoA esters. Required for proper phospholipid and, to a lower extent, galactolipid composition.
Gene References into Functions
  1. ACBP2, which shows high (76.9%) conservation in amino acid homology to ACBP1, did not appear to be involved in the freezing response. PMID: 20404541
  2. These observations support a positive role for ACBP2 in promoting abscissic acid signalling in germination, seedling development and the drought response. PMID: 22788984
  3. ACBP2 can mediate tolerance to Cd(II)-induced oxidative stress by interacting with two protein partners, AtFP6 and lysoPL2. PMID: 20657176
  4. ACBP2 can bind lysoPL2 to promote the degradation of lysophosphatidylcholine in response to Cd-induced oxidative stress. PMID: 20345607
  5. ACBP1 and ACBP2 are essential in lipid transfer during early embryogenesis in Arabidopsis. PMID: 20345632
  6. observed to interact with AtFP6...an ACBP2 derivative lacking ankyrin repeats did not interact with AtFP6, indicating that the ankyrin repeats mediate interaction; plants overexpressing ACBP2 or AtFP6 were more tolerant to Cd(II) than wild-type plants. PMID: 18823312

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Subcellular Location
Cell membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein. Peroxisome membrane; Single-pass membrane protein.
Protein Families
ACBP family
Tissue Specificity
Mostly expressed in roots and flowers, and, to a lower extent, in stems, pods and leaves (at protein level).
Database Links

KEGG: ath:AT4G27780

STRING: 3702.AT4G27780.1

UniGene: At.25382

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