apolpp Antibody

Code CSB-PA893707XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) apolpp Polyclonal antibody
Uniprot No.
Target Names
apolpp
Alternative Names
apolpp antibody; Rfabg antibody; RfaBp antibody; CG11064Apolipophorins antibody; Retinoid- and fatty acid-binding glycoprotein) [Cleaved into: Apolipophorin-2 antibody; ApoL2 antibody; Apolipophorin II antibody; ApoLII); Apolipophorin-1 antibody; ApoL1 antibody; Apolipophorin I antibody; ApoLI)] antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) apolpp protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Constitutes the major component of lipophorin, which mediates transport for various types of lipids in hemolymph. Acts by forming lipoprotein particles that bind lipoproteins and lipids. Also involved in the transport of hydrophobic ligands like juvenile hormones, pheromone hydrocarbons and carotenoids. Required for morphogens wingless (wg) and hedgehog (hh) function, probably by acting as vehicles for the movement of wg and hh, explaining how covalently lipidated wg and hh can spread over long distances. May also be involved in transport and/or metabolism of heme.
Gene References into Functions
  1. Wingless, Hedgehog and glycophosphatidylinositol-linked proteins copurify with lipophorin, and co-localize with it in the developing wing epithelium of Drosophila. PMID: 15875013
Subcellular Location
Secreted. Note=Secreted in hemolymph.
Tissue Specificity
During stage 12, it is highly present throughout the yolk sac. By late stage 14, it localizes in the lateral fat body cells. Starting at stage 14, it localizes to the apodemes. Component of hemolymph clots (at protein level). Expressed in the amniosera.
Database Links

KEGG: dme:Dmel_CG11064

STRING: 7227.FBpp0088252

UniGene: Dm.1647

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