ARC6 Antibody

Code CSB-PA887765XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) ARC6 Polyclonal antibody
Uniprot No.
Target Names
ARC6
Alternative Names
ARC6; At5g42480; MDH9.18; Protein ACCUMULATION AND REPLICATION OF CHLOROPLASTS 6, chloroplastic
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana ARC6 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Component of the plastid division machinery. Involved in the initiation of proplastid and plastid division (including chloroplasts, statoliths and leukoplasts). Promotes the assembly and/or stabilization of the plastid-dividing FtsZ ring, functioning as an antagonistic regulator of FtsZ dynamics against CDP1. Relays plastid division site position between stroma and outer surface via interactions with the stromal FtsZ ring and the outer membrane PDV2 that recruits cytoplasmic ARC5 ring. Required for plastid equatorial positioning of PDV2 and ARC5. May contribute to gravitropism in stems and hypocotyls. Seems to influence stromule (stroma-filled tubular extensions of the plastid envelope membrane) length and frequency.
Gene References into Functions
  1. The ARC6 intermembrane space region bears a structurally uncharacterized domain of unknown function, DUF4101, that is highly conserved among ARC6 and Ftn2 proteins. This study reports the crystal structure of this domain. PMID: 26452626
  2. These results suggest that besides ARC6-mediated anchoring, an additional FtsZ-anchoring mechanism is present in chloroplasts. PMID: 23578755
  3. The effect of reduced chloroplast number on the photosynthetic competence of leaves of A. thaliana with mutations at accumulation and replication of chloroplasts (ARC) sites ARC3, ARC5, and ARC6 are reported. PMID: 16170638
  4. alteration in stromule length in arc3 and arc6 mutants occurred despite wild-type plastid densities PMID: 18764889
Subcellular Location
Plastid, chloroplast inner membrane; Single-pass membrane protein. Note=Localized to a ring at the center of the chloroplasts (equatorial positioning) prior to and during constriction.
Database Links

KEGG: ath:AT5G42480

STRING: 3702.AT5G42480.1

UniGene: At.30169

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