ARP6 Antibody

Code CSB-PA818595XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) ARP6 Polyclonal antibody
Uniprot No.
Target Names
ARP6
Alternative Names
ARP6 antibody; ESD1 antibody; SUF3 antibody; At3g33520 antibody; T4P3.8Actin-related protein 6 antibody; Protein EARLY IN SHORT DAYS 1 antibody; Protein SUPPRESSOR OF FRIGIDA 3 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana ARP6 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant H2A.F/Z leading to transcriptional regulation of selected genes (e.g. FLC) by chromatin remodeling. Binds to the promoter region of FLC chromatin. Required for the activation of FLC and FLC/MAF genes expression to levels that inhibit flowering, through both histone H3 and H4 acetylation and methylation mechanisms. Involved in several developmental processes including organization of plant organs, leaves formation, flowering time repression, and fertility. Modulates photoperiod-dependent epidermal leaves cell development; promotes cell division in long days, and cell expansion/division in short days. May be involved in the regulation of pathogenesis-related proteins (PRs).
Gene References into Functions
  1. ARP6 is required for proper H2A.Z deposition at a number of Pi starvation response (PSR) genes in Arabidopsis. [ARP6] PMID: 19897606
  2. ARP6 acts in the nucleus to regulate plant development, and it does so through modulation of chromatin structure and the control of gene expression.[AtARP6] PMID: 16141450
  3. ESD1 encodes ATARP6, a putative component of chromatin remodelling that positively regulates FLC accumulation. PMID: 16495307
Subcellular Location
Nucleus. Cytoplasm. Note=Localized in the nucleus during the interphase, but is released into the cytoplasm during the mitotic phase (PubMed:16141450). Associated to heterochromatin (PubMed:16141450). Localized at the nuclear periphery when interacting with SWC6 (PubMed:16155178, PubMed:17470967).
Protein Families
Actin family, ARP6 subfamily
Tissue Specificity
Mostly expressed in flowers, and, to a lower extent, in seedlings, shoot apex, stems, siliques, seeds, and roots (at protein level).
Database Links

KEGG: ath:AT3G33520

STRING: 3702.AT3G33520.1

UniGene: At.18479

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