Code | CSB-PA002283XA01STA |
Size | Pls inquire |
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Full Product Name | Rabbit anti-Saccharomyces cerevisiae (strain YJM789) (Baker's yeast) ATG12 Polyclonal antibody |
Uniprot No. | A6ZLF7 |
Target Names | ATG12 |
Alternative Names | ATG12 antibody; APG12 antibody; SCY_0427Ubiquitin-like protein ATG12 antibody; Autophagy-related protein 12 antibody |
Raised in | Rabbit |
Species Reactivity | Saccharomyces cerevisiae (strain YJM789) (Baker's yeast) |
Immunogen | Recombinant Saccharomyces cerevisiae (strain YJM789) (Baker's yeast) ATG12 protein |
Immunogen Species | Saccharomyces cerevisiae (strain YJM789) (Baker's yeast) |
Conjugate | Non-conjugated |
Clonality | Polyclonal |
Isotype | IgG |
Purification Method | Protein A/G |
Concentration | It differs from different batches. Please contact us to confirm it. |
Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Form | Liquid |
Tested Applications | ELISA, WB (ensure identification of antigen) |
Protocols | ELISA Protocol |
Troubleshooting and FAQs | Antibody FAQs |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Value-added Deliverables | ① 200ug * antigen (positive control); ② 1ml * Pre-immune serum (negative control); |
Quality Guarantee | ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection; ② ELISA titer can be guaranteed 1: 64,000; ③ WB validation with antigen can be guaranteed positive; |
Lead Time | Made-to-order (14-16 weeks) |
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Function (From Uniprot) |
Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate functions as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes. ATG12-ATG5 rearranges the ATG3 catalytic center and enhances its E2 activity. |
Subcellular Location | Preautophagosomal structure membrane; Peripheral membrane protein. |
Protein Families | ATG12 family |