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Your Good Partner in Biology Research
| Code | CSB-PA891592XA01SXV |
| Size | Pls inquire |
| Have Questions? | Leave a Message or Start an on-line Chat |
| Full Product Name | Rabbit anti-Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) atg12 Polyclonal antibody |
| Uniprot No. | Q9US24 |
| Target Names | atg12 |
| Alternative Names | atg12 antibody; SPAC1783.06cUbiquitin-like protein ATG12 antibody; Autophagy-related protein 12 antibody |
| Raised in | Rabbit |
| Species Reactivity | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
| Immunogen | Recombinant Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) atg12 protein |
| Immunogen Species | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
| Conjugate | Non-conjugated |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification Method | Protein A/G |
| Concentration | It differs from different batches. Please contact us to confirm it. |
| Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Form | Liquid |
| Tested Applications | ELISA, WB (ensure identification of antigen) |
| Protocols | ELISA Protocol |
| Troubleshooting and FAQs | Antibody FAQs |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Value-added Deliverables | ① 200ug * antigen (positive control); ② 1ml * Pre-immune serum (negative control); |
| Quality Guarantee | ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection; ② ELISA titer can be guaranteed 1: 64,000; ③ WB validation with antigen can be guaranteed positive; |
| Lead Time | Made-to-order (14-16 weeks) |
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| Function (From Uniprot) |
Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. Conjugation with atg5 through a ubiquitin-like conjugating system involving also atg7 as an E1-like activating enzyme and atg10 as an E2-like conjugating enzyme, is essential for its function. The atg12-atg5 conjugate functions as an E3-like enzyme which is required for lipidation of atg8 and atg8 association to the vesicle membranes. Plays a role in meiosis and sporulation. |
| Subcellular Location | Cytoplasm. Nucleus. Preautophagosomal structure membrane; Peripheral membrane protein. |
| Protein Families | ATG12 family |
| Database Links |
KEGG: spo:SPAC1783.06c STRING: 4896.SPAC1783.06c.1 |
