AUR3 Antibody

Datasheet

Code	CSB-PA528946XA01DOA
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Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) AUR3 Polyclonal antibody

Uniprot No.

O64629

Target Names

AUR3

Alternative Names

AUR3 antibody; At2g45490 antibody; F17K2.2Serine/threonine-protein kinase Aurora-3 antibody; AtAur3 antibody; EC 2.7.11.1 antibody; Aurora-like kinase 3 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana AUR3 protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Phosphorylates in vitro histone H3 at 'Ser-10' (H3S10ph) and 'Ser-28' (H3S28ph), but not at 'Thr-3' (H3T3ph) or 'Thr-11' (H3T11ph). Colocalizes with phosphorylated histone H3 during mitosis. Associates with cytoskeletal structures that are necessary for cytokinesis and with the microtubule spindle.

Gene References into Functions

AtAUR1 and AtAUR3 have both redundant and distinct functions through interactions with transcription factors (TFs). In addition, database analysis revealed that most of the highly AtAUR-interacting TFs contained a detectable phosphopeptide that was consistent with the consensus motifs for human AURs, suggesting that these TFs are substrates of the AtAURs. PMID: 27734173
Aurora kinase AtAUR3 showed dot-like distribution on condensed chromosomes at prophase and then localized at the metaphase plate, and overexpression of AtAUR3 induces disassembly of spindle microtubules and alteration of orientation of cell division. PMID: 16028112

Subcellular Location

Cytoplasm, perinuclear region. Nucleus. Chromosome. Chromosome, centromere.

Protein Families

Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily

Tissue Specificity

Abundant in roots, flowers and flower buds, low or absent in expanded leaves, stems and siliques.

Database Links

KEGG: ath:AT2G45490

STRING: 3702.AT2G45490.1

UniGene: At.37011

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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AUR3 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background