BNR1 Antibody

Code CSB-PA331171XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) BNR1 Polyclonal antibody
Uniprot No.
Target Names
BNR1
Alternative Names
BNR1 antibody; YIL159WBNI1-related protein 1 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) BNR1 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
May organize microtubules by mediating spindle positioning and movement in the budding process. Potential target of the RHO family members.
Gene References into Functions
  1. Smy1 regulation of Bnr1 activity is required for efficient secretory vesicle traffic. PMID: 26764093
  2. F-actin stabilization is regulated by yeast formins Bni1p and Bnr1p PMID: 23653364
  3. Bnr1p has two separable regions that each contribute to its bud neck localization PMID: 20147448
  4. different formin isoforms have roles in maintaining stable and dynamic axes in the same yeast cell PMID: 15371545
  5. Bnr1 was confined to the bud neck and did not exchange with a cytoplasmic pool. PMID: 17344480
  6. Yeast expressing the nonlocalized actin nucleating/assembly formin homology (FH) 1-FH2 domains of Bnr1p or Bni1p as the sole formin grow well. PMID: 19297522

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Protein Families
Formin homology family, BNI1 subfamily
Database Links

KEGG: sce:YIL159W

STRING: 4932.YIL159W

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