BRACA Antibody

Datasheet
Code CSB-PA237357XA01DIL
Product Type Polyclonal Antibody
Uniprot No. Q07998
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) BRACA protein
Raised in Rabbit
Species Reactivity Danio rerio (Zebrafish) (Brachydanio rerio)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Brachyury protein homolog A (No tail protein A) (No tail protein) (Protein T homolog A) (T-box protein ZfT) (Zf-T) ntla ntl t
Immunogen Species Danio rerio (Zebrafish) (Brachydanio rerio)
Gene Names ntla
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Involved in the transcriptional regulation of genes required for mesoderm differentiation, including itself. Indispensable for the formation of the notochord and the tail structure. Functions together with tbx16/spadetail in development of trunk and tail mesoderm. Functions by itself early in development to repress medial floor plate and promote notochord fate but at later times, functions together with tbx16/spadetail to promote medial floor plate formation. Acts in a parallel pathway to, but cooperates with, non-canonical wnt-signaling during tail formation. Required for the morphogenesis of Kupffer's vesicle and regulates left-right asymmetry.
Subcellular Location Nucleus
Tissue Specificity First expressed at the dorsal side of the blastula embryo. Expressed in the germ ring, shield and chordamesoderm during gastrulation and is restricted to the notochord and tailbud during somitogenesis (at protein level).
Database Links

KEGG: dre:30399

STRING: 7955.ENSDARP00000005351

UniGene: Dr.1468

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