BT2 Antibody

Code CSB-PA856726XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) BT2 Polyclonal antibody
Uniprot No.
Target Names
BT2
Alternative Names
BT2 antibody; At3g48360 antibody; T29H11.120BTB/POZ and TAZ domain-containing protein 2 antibody; BTB and TAZ domain protein 2 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana BT2 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Plays a key role as a component of the TAC1-mediated telomerase activation pathway certainly by targeting a telomerase repressor to degradation. Seems to occupy an integral position in a complex signaling network that perceives, integrates, and responds to multiple, and sometimes competing, signals. Enhances responses to auxin in postgermination and vegetative development. Also negatively regulates ABA- and sugar-mediated inhibition of the germination. Essential for female and male gametophyte development.
Gene References into Functions
  1. the roles of BT2-interacting partners GTE9 and GTE11, bromodomain and extraterminal-domain proteins of Global Transcription Factor Group E, in BT2-mediated responses to sugars and hormones, are reported. PMID: 29363002
  2. direct activation of BT1 and BT2 by NLP transcriptional activators is a key component of the molecular mechanism underlying the nitrate response in Arabidopsis PMID: 28025145
  3. BT1 and BT2 act as conserved negative regulators of nitrate uptake genes and nitrogen use efficiency in plants PMID: 27208309
  4. BT1, BT2 and BT3 act redundantly during gametophyte development. PMID: 19054356
  5. BT2, a protein with BTB, TAZ, and calmodulin binding domains, is an essential component of the TAC1-mediated telomerase activation pathway. [BT2] PMID: 17220202
  6. BT2 is a central component of an interconnected signaling network that detects and responds to multiple inputs. PMID: 19525324

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Subcellular Location
Nucleus. Cytoplasm.
Tissue Specificity
Preferentially expressed in young leaves and roots.
Database Links

KEGG: ath:AT3G48360

STRING: 3702.AT3G48360.1

UniGene: At.21922

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