BZIP60 Antibody

Code CSB-PA874912XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) BZIP60 Polyclonal antibody
Uniprot No.
Target Names
BZIP60
Alternative Names
BZIP60; At1g42990; F13A11.5; bZIP transcription factor 60; AtbZIP60
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana BZIP60 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Transcription factor involved in the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Plays a role in plant immunity and abiotic stress responses.
Gene References into Functions
  1. RLG1 proteins derived from transgene were mainly found in the cytoplasm; however, some were in the microsomal fraction, possibly on the ER membrane. PMID: 26820526
  2. bZIP60 binds directly to UPRE-III-containing DNA, and regulates NAC103. PMID: 23869562
  3. overexpression of the AtbZIP60 gene in transgenic cell lines improved salt, drought, and cold stress tolerances by regulating expression of Ca(2+)-dependent protein kinase genes. PMID: 23275191
  4. AtPDI gene expression was investigated in different tissues, in response to chemically induced unfolded protein response (UPR), and in null mutants of UPR signaling mediators (AtIRE1-2 and AtbZIP60). PMID: 18574595
  5. bZIP60 is involved in the plant endoplasmic reticulum stress response and is upregulated during normal development in anther cells. [bZIP60] PMID: 19017746
  6. possible mechanisms of AtbZIP60's action in the nucleus are discussed PMID: 19352029

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Subcellular Location
[Isoform 1]: Endoplasmic reticulum membrane; Single-pass membrane protein.; [Isoform 2]: Nucleus. Note=The bZIP domain is translocated into the nucleus in response to ER stress.
Protein Families
BZIP family
Tissue Specificity
Expressed in seedlings, rosette and cauline leaves, stems, buds, flowers, siliques, immature seeds, anthers and pollen grains.
Database Links

KEGG: ath:AT1G42990

STRING: 3702.AT1G42990.1

UniGene: At.21271

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