Beta-insect excitatory toxin LqqIT1 Antibody

Code CSB-PA324858ZA01LDT
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Product Details

Full Product Name
Rabbit anti-Leiurus quinquestriatus quinquestriatus (Egyptian scorpion) (Deathstalker scorpion) Beta-insect excitatory toxin LqqIT1 Polyclonal antibody
Uniprot No.
Target Names
Beta-insect excitatory toxin LqqIT1
Alternative Names
Beta-insect excitatory toxin LqqIT1 (Insect toxin 1) (LqqIT1')
Raised in
Rabbit
Species Reactivity
Leiurus quinquestriatus quinquestriatus
Immunogen
Recombinant Leiurus quinquestriatus quinquestriatus Beta-insect excitatory toxin LqqIT1 protein
Immunogen Species
Leiurus quinquestriatus quinquestriatus (Egyptian scorpion) (Deathstalker scorpion)
Conjugate
Non-conjugate
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

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Target Background

Function
Excitatory insect beta-toxins induce a spastic paralysis. They bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing. This toxin induces a fast excitatory contraction paralysis on fly larvae. It is active only on insects.
Subcellular Location
Secreted.
Protein Families
Long (4 C-C) scorpion toxin superfamily, Sodium channel inhibitor family, Beta subfamily
Tissue Specificity
Expressed by the venom gland.
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