C1GalTA Antibody

Code CSB-PA748703XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) C1GalTA Polyclonal antibody
Uniprot No.
Target Names
C1GalTA
Alternative Names
C1GalTA antibody; CG9520 antibody; Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 antibody; EC 2.4.1.122 antibody; Core 1 O-glycan T-synthase antibody; Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1 antibody; Core 1 beta1,3-galactosyltransferase 1 antibody; C1GalT1 antibody; Core 1 beta3-Gal-T1 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) C1GalTA protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins.
Gene References into Functions
  1. T3lec, but not T2lec and T4lec, had a clear activating effect on Drosophila melanogaster core 1 galactosyltransferase enzyme activity PMID: 27738109
  2. named the CG9520 gene Drosophila core 1 beta1,3-galactosyltransferase 1 because it is responsible for the synthesis and function of T antigen in vivo. PMID: 18824562
  3. Lectin staining and blotting experiments confirmed that core 1 galactosyltransferase contributes to the synthesis of Gal-beta1,3-GalNAc in vivo PMID: 18985719
Subcellular Location
Membrane; Single-pass type II membrane protein.
Protein Families
Glycosyltransferase 31 family, Beta3-Gal-T subfamily
Tissue Specificity
In stage 12 embryos, expression is seen in the amnioserosa and by stage 16, also in the central nervous system, predominantly the ventral nerve cord and brain. Also in embryos, preferential expression is seen in the ejaculatory duct and the nurse cells (b
Database Links

KEGG: dme:Dmel_CG9520

STRING: 7227.FBpp0079388

UniGene: Dm.366

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