caz Antibody

Code CSB-PA631662XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) caz Polyclonal antibody
Uniprot No.
Target Names
caz
Alternative Names
caz antibody; SARFH antibody; CG3606RNA-binding protein cabeza antibody; P19 antibody; Sarcoma-associated RNA-binding fly homolog antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) caz protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
May participate in a function common to the expression of most genes transcribed by RNA polymerase II.
Gene References into Functions
  1. Results that the molecular mechanisms controlling the nuclear import of FUS/Caz and FUS autoregulation are conserved between humans and Drosophila PMID: 25447237
  2. Data demonstrate that FUS/Caz regulates neuromuscular junction development and plays an evolutionarily conserved role in modulating the strength of synaptic transmission in motor neurons. PMID: 24569165
  3. The loss of caz in Drosophila led to severe growth defects in the eyes and ventral nerve cords, caused locomotive disability and neuromuscular junction disruption, but did not induce apoptotic cell death. PMID: 22443542
Subcellular Location
Nucleus.
Protein Families
RRM TET family
Tissue Specificity
Ubiquitous. Enriched in the brain and central nervous system during embryogenesis. Enriched in the adult head. Embryos contain both isoforms A and B, whereas later in development (heads and torsos) only isoform B is detected.
Database Links

KEGG: dme:Dmel_CG3606

STRING: 7227.FBpp0073996

UniGene: Dm.2872

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