CDC123 Antibody

Code CSB-PA180372XA01SVG
Size Enquire
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) CDC123 Polyclonal antibody
Uniprot No.
Target Names
CDC123
Alternative Names
CDC123 antibody; YLR215C antibody; Cell division cycle protein 123 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) CDC123 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Regulates the cell cycle in a nutrient dependent manner. Accumulates in presence of nutrients and directs the destabilization of DMA1 and DMA2, whose accumulation results in a G1 block. Regulates also the abundance of GCD11 an essential component of the translational initiation factor 2.
Gene References into Functions
  1. CDC123 may have a role in novel protein modifications PMID: 25976611
  2. Data indicate that Cdc123 is a specific assembly factor for eukaryotic translation initiation factor 2 (eIF) subunit alpha (sui2), subunit beta (sui3) and subunit gamma (GCD11), which is indispensable for the onset of protein synthesis. PMID: 23775072
  3. the Cdc123-Chf-Gcd11 axis is an essential pathway for nutritional control of START that runs parallel to the Tor-Gcn2-Sui2 system of translational control PMID: 15319434
Subcellular Location
Cytoplasm.
Protein Families
CDC123 family
Database Links

KEGG: sce:YLR215C

STRING: 4932.YLR215C

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1