Cf2 Antibody

Code CSB-PA321800XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Cf2 Polyclonal antibody
Uniprot No.
Target Names
Cf2
Alternative Names
Cf2 antibody; CG11924 antibody; Chorion transcription factor Cf2 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Cf2 protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Transcriptional regulator; binds to the promoter region of Cp15. Also binds to its own promoter, thus having a probable autoregulatory role.
Gene References into Functions
  1. CF2 expression variations yield altered Mef2 expression levels but with correct spatio-temporal Mef2 expression patterns, it can be concluded that only the mechanism controlling expression levels is de-regulated. Here, it is proposed that CF2 regulates Mef2 expression through a Feedforward Loop circuit. PMID: 28617826
  2. These results indicate a role for CF2 as a direct negative regulator of the thin filament protein gene Actin 88F. PMID: 20520827
  3. CF2 expression during muscle development is dependent on the myogenic factor MEF2. PMID: 12204268
  4. Mef2 and Cf2 collaborate in activation of the myogenic program in Drosophila. PMID: 18160709
  5. CF2 depletion alters the relative expression of thin and thick filament components of muscle. PMID: 18448314

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Subcellular Location
Nucleus.
Tissue Specificity
Isoform I is found in embryos, pupae and adult somatic tissue; isoform II occurs in embryos, pupae, ovaries, testis and to a lesser extent in adult somatic tissue.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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