CPFTSY Antibody

Code CSB-PA529291XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) CPFTSY Polyclonal antibody
Uniprot No.
Target Names
CPFTSY
Alternative Names
CPFTSY antibody; FTSY antibody; At2g45770 antibody; F4I18.25Cell division protein FtsY homolog antibody; chloroplastic antibody; Chloroplast SRP receptor homolog antibody; alpha subunit CpFtsY antibody; Fused signal recognition particle receptor antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana CPFTSY protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Signal recognition particle receptor protein. Binds GTP specifically. The GTPase activity is inhibited by the N-terminus of the protein until binding to the thylakoid membrane. Activates the GTPase activity of FFC/cpSRP54 when bound to the cpSRP complex. Required for light-harvesting chlorophyll a/b-binding protein (LHCP) integration into thylakoids. Might be also functionally linked to the Sec translocation machinery.
Gene References into Functions
  1. Mutations within the cpFtsY gene are associated with an inability to induce Fe(III) chelate reductase activity in response to iron deficiency. PMID: 16813577
  2. These results highlight intriguing differences between the classical and chloroplast SRP and SRP receptor GTPases, and help explain how the chloroplast SRP pathway can mediate efficient targeting of proteins to the thylakoid membrane. PMID: 17475780
  3. the crystal structure of chloroplast FtsY (cpFtsY) at 1.75 A resolution. PMID: 18022392
  4. cpftsY mutants generally exhibit defects in the biogenesis of light-harvesting chlorophyll proteins and other thylakoidal membrane proteins that are less severe than in the alb3 mutants. PMID: 18764927
  5. cpFtsY membrane-binding motif plays a critical role in the intramolecular communication that regulates cpSRP receptor functions at the membrane. PMID: 19293157

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Subcellular Location
Plastid, chloroplast stroma. Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side. Note=The membrane-binding domain is capable of partial insertion into the lipid bilayer.
Protein Families
GTP-binding SRP family
Tissue Specificity
Expressed in green tissues. Low levels in roots and seeds.
Database Links

KEGG: ath:AT2G45770

STRING: 3702.AT2G45770.2

UniGene: At.491

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