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| Code | CSB-PA530076XA01SXV |
| Size | US$299 |
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The clr6 polyclonal antibody is generated by immunizing a rabbit with a recombinant Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) clr6 protein (1-239aa), leading to the production of specific antibodies in the rabbit's IgG-rich serum. Subsequently, the produced clr6 antibody is subjected to affinity chromatography purification. This resulting clr6 antibody exhibits reactivity with Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) clr6 protein and has been rigorously validated for functionality in both ELISA and WB applications.
The clr6 is a histone deacetylase enzyme, which functions as a key component of the clr6 complex in fission yeast. This complex is responsible for removing acetyl groups from histone proteins, leading to chromatin condensation and gene silencing. The clr6 protein, through its deacetylase activity, plays a critical role in maintaining proper chromatin structure, repressing transcription of specific genes, and regulating various cellular processes, including cell cycle progression and response to environmental cues.
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KEGG: spo:SPBC36.05c
STRING: 4896.SPBC36.05c.1
