CkIIbeta Antibody

Code CSB-PA006075XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) CkIIbeta Polyclonal antibody
Uniprot No.
Target Names
CkIIbeta
Alternative Names
CkIIbeta antibody; Cask-II-b antibody; CG15224Casein kinase II subunit beta antibody; CK II beta antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) CkIIbeta protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Participates in Wnt signaling. Plays a complex role in regulating the basal catalytic activity of the alpha subunit.
Gene References into Functions
  1. Data (including data from studies using transgenic animals) suggest that catalytic activity of casein kinase 2 (CkIIa/CkIIb) is essential for oogenesis in this species; Jabba, a lipid droplet-associated protein and substrate for casein kinase 2, is essential in modulating ovarian lipid metabolism. (CkIIa = casein kinase II alpha subunit; CkIIb = casein kinase II beta subunit) PMID: 29326167
  2. Drosophila splicing factor P element Somatic Inhibitor (PSI) is phosphorylated at at least two different sites by at minimum two different kinases, casein kinase II (CK II) and tousled-like kinase (tlk). PMID: 23437125
  3. Coexpressing CK2alpha and CK2beta increases Smo accumulation and induces ectopic Hh target gene expression. PMID: 20876583
  4. Identification and characterization of proteins that interact with Drosophila melanogaster protein kinase CK2 PMID: 11827179
  5. ZFP47 is a new physiological partner and substrate of CK2. PMID: 11827180
  6. CK2(beta)tes encodes a testis-specific isoform of the regulatory subunit of casein kinase 2 PMID: 11874456
  7. This study implicates a role for DmCK2beta in cell proliferation or cell survival during brain development. PMID: 12406573
  8. results reveal a potential mechanism for regulation of the dMi-2 enzyme and point toward CK2 phosphorylation as a common feature of CHD family ATPases PMID: 16223721
  9. The DmCK2beta transcription unit encodes for functionally non-redundant protein isoforms. PMID: 16530986

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Protein Families
Casein kinase 2 subunit beta family
Database Links

KEGG: dme:Dmel_CG15224

STRING: 7227.FBpp0089135

UniGene: Dm.142

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