ctr4 Antibody

Code CSB-PA530961XA01SXV
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Product Details

Full Product Name
Rabbit anti-Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) ctr4 Polyclonal antibody
Uniprot No.
Target Names
ctr4
Alternative Names
ctr4; SPCC1393.10; Copper transport protein ctr4; Copper transporter 4
Raised in
Rabbit
Species Reactivity
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Immunogen
Recombinant Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) ctr4 protein
Immunogen Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Required for high affinity copper (probably reduced Cu I) transport into the cell.
Gene References into Functions
  1. The authors propose that the Ctr4 central domain mediates Cu transport in this hetero-complex, whereas the Ctr5 carboxyl-terminal domains functions in the regulation of trafficking of the Cu transport complex to the cell surface. [Ctr4 & Ctr5] PMID: 21273250
  2. Ctr4 and Ctr5 proteins co-localize at the plasma membrane shortly after meiotic induction, whereas Ctr6 is located on the membrane of vacuoles. PMID: 24569997
  3. a copper-dependent internalization and recycling of the heteromeric Ctr4-Ctr5 complex PMID: 20694150
Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
Copper transporter (Ctr) (TC 1.A.56) family, SLC31A subfamily
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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