Cd101 Antibody

Code CSB-PA423295ZA01MO
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Product Details

Full Product Name
Rabbit anti-Mus musculus (Mouse) Cd101 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
Cd101 antibody; Igsf2 antibody; Immunoglobulin superfamily member 2 antibody; IgSF2 antibody; Glu-Trp-Ile EWI motif-containing protein 101 antibody; EWI-101 antibody; CD antigen CD101 antibody
Raised in
Species Reactivity
Mus musculus
Recombinant Mus musculus Cd101 protein
Immunogen Species
Mus musculus (Mouse)
Purification Method
Protein A/G
It differs from different batches. Please contact us to confirm it.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Tested Applications
ELISA, WB (ensure identification of antigen)
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

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Target Background

Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells.
Gene References into Functions
  1. CD101 inhibits the expansion of colitogenic T cells. PMID: 26813346
  2. Further support is provided for the hypothesis that Cd101 is insulin-dependent diabetes susceptibility region 10 (Idd10); haplotype and expression analyses of novel Idd10 congenic strains are coupled to the development of a CD101 knockout mouse. PMID: 21613616
  3. A gene region (Idd10) previously shown to influence susceptibility to type 1 diabetes in the NOD mouse also influences an autoimmune disease involving a different tissue, the liver, which follows an infection with Novosphingobium aromaticivorans. PMID: 21613619
Subcellular Location
Membrane; Single-pass type I membrane protein.
Database Links
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