CD101

CD101, also known as immunoglobulin superfamily member 2, is a type I transmembrane glycoprotein. It is commonly referred to as IGSF2 or V7. Functionally, CD101 negatively regulates T - cell activation and proliferation. It participates in the T - cell receptor signaling pathway, modulating the immune response.
In terms of disease association, CD101 has been linked to autoimmune diseases and certain types of cancers. Regarding drug development, there is ongoing research to design agents targeting CD101 to either enhance immune responses against tumors or suppress over - active immune reactions in autoimmune conditions.