dhs-21 Antibody

Code CSB-PA636400XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans dhs-21 Polyclonal antibody
Uniprot No.
Target Names
dhs-21
Alternative Names
dhs-21 antibody; R11D1.11L-xylulose reductase antibody; XR antibody; EC 1.1.1.10 antibody; Dicarbonyl/L-xylulose reductase antibody; DCXR antibody; Short-chain dehydrogenase 21 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans dhs-21 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Catalyzes the NADPH-dependent reduction of L-xylulose, D-xylulose, L-(+) erythrulose, D-erythrose, D-threose, L-ribulose, 1,4-dibromo-2,3-butanedione and 2,3-heptanedione. Also active against isatin, 9,10-phenanthrenequinone, menadione, 2,3-hexaenadione and 3,4-hexahenadione. No activity observed when tested using NADH rather than NADPH.
Gene References into Functions
  1. Results suggest that DHS-21 is a bona fide DCXR of C. elegans, essential for normal life span and reproduction. PMID: 21477590
Subcellular Location
Cell membrane.
Protein Families
Short-chain dehydrogenases/reductases (SDR) family
Tissue Specificity
Expressed in intestine, gonad and spermatids (at protein level). Expressed in intestine, uterine seam, gonadal sheath cells, spermathecal-uterus valve and spermatids.
Database Links

KEGG: cel:CELE_R11D1.11

STRING: 6239.R11D1.11

UniGene: Cel.2795

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