DREB1C Antibody

Code CSB-PA871211XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) DREB1C Polyclonal antibody
Uniprot No.
Target Names
DREB1C
Alternative Names
DREB1C antibody; CBF2 antibody; ERF030 antibody; At4g25470 antibody; M7J2.161 antibody; Dehydration-responsive element-binding protein 1C antibody; Protein DREB1C antibody; C-repeat/dehydration-responsive element-binding factor 2 antibody; C-repeat-binding factor 2 antibody; CRT/DRE-binding factor 2 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana DREB1C protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates cold-inducible transcription. CBF/DREB1 factors play a key role in freezing tolerance and cold acclimation.
Gene References into Functions
  1. This study reveals the essential functions of C-repeat binding factors (CBF) in chilling stress response and cold acclimation, as well as defines a set of genes as CBF regulon. PMID: 27353960
  2. CBFs play an important role in the trade-off between cold tolerance and plant growth through the precise regulation of COR genes in the complicated transcriptional network. PMID: 28009483
  3. the three CBF genes together are required for cold acclimation and freezing tolerance. PMID: 27252305
  4. Data indicate that the C-repeat binding factor (CBF) locus includes three genes - CBF1, CBF2 and CBF3 (AT4G25480) - that are induced by low temperature and encode transcription factors. PMID: 26369909
  5. A major locus harboring three cold-responsive transcription factor genes CBF1, was identified. PMID: 23721132
  6. Studies indicate that DREB1A (CBF3), DREB1B (CBF1) and DREB1C (CBF2) play an important role in increasing stress tolerance. PMID: 23271026
  7. Transcriptional changes in cell wall metabolism-related components under overexpression of a key transcription factor for freezing tolerance, CBF2, were identified. PMID: 21611181
  8. Overexpression of CBF2 in Arabidopsis suppressed the responsiveness of leaf tissues to ethylene compared with that in wild-type plants, as manifested in significantly delayed senescence and chlorophyll degradation. PMID: 20636906
  9. These results indicate that overexpression of CBF2 not only increases frost tolerance, but also affects other developmental processes. PMID: 19854800
  10. SOC1 Directly Represses the Expression of CBF2 Genes. PMID: 19825833
  11. PIF7 functions as a transcriptional repressor for DREB1C expression and its activity is regulated by PIF7-interacting factors TIMING OF CAB EXPRESSION1 and Phytochrome B. PMID: 19837816
  12. We explored the regulation of CBF1-3 by the circadian clock. PMID: 15728337
  13. The low freezing tolerance of FTQ4-Cvi (FREEZING TOLERANCE QTL 4) alleles was associated with a deletion of the promoter region of Cvi CBF2, and with low RNA expression of CBF2 and of several CBF target genes. PMID: 16244146
  14. CBF1 and CBF3, but not CBF2 have a concerted additive effect to induce the whole CBF regulon and the complete development of cold acclimation PMID: 18093929
  15. Important evolutionary changes in CBF1, -2, and -3 may have primarily occurred at the level of gene regulation as well as in protein function. PMID: 18990244

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Subcellular Location
Nucleus.
Protein Families
AP2/ERF transcription factor family, ERF subfamily
Tissue Specificity
Expressed in leaves and roots.
Database Links

KEGG: ath:AT4G25470

STRING: 3702.AT4G25470.1

UniGene: At.233

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