DUG1 Antibody

Code CSB-PA331893XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DUG1 Polyclonal antibody
Uniprot No.
Target Names
DUG1
Alternative Names
DUG1 antibody; YFR044C antibody; Cys-Gly metallodipeptidase DUG1 antibody; EC 3.4.13.- antibody; Deficient in utilization of glutathione protein 1 antibody; GSH degradosomal complex subunit DUG1 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DUG1 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Catalytic component of the GSH degradosomal complex involved in the degradation of glutathione (GSH) and other peptides containing a gamma-glu-X bond. Functions also in a DUG2-DUG3-independent manner as a dipeptidase with high specificity for Cys-Gly and no activity toward tri- or tetrapeptides.
Gene References into Functions
  1. Overexpression of cDNAs is a promising approach to engineer S. cerevisiae metabolism; here DUG1 overexpression lead to enhance growth of non-ethanol producing S. cerevisiae strains lacking pyruvate decarboxylases. PMID: 29636254
  2. Structural similarity between the Dug1p-peptide complex and the bestatin-bound complex of CN2 suggests that the Dug1p-peptide structure can be used as a template for designing natural peptide inhibitors. PMID: 25427234
  3. The Dug1p family represents a novel class of Cys-Gly dipeptidases. PMID: 19346245
Subcellular Location
Cytoplasm. Mitochondrion.
Protein Families
Peptidase M20A family
Database Links

KEGG: sce:YFR044C

STRING: 4932.YFR044C

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