dvr1 Antibody

Code CSB-PA330463XA01DIL
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Product Details

Full Product Name
Rabbit anti-Danio rerio (Zebrafish) (Brachydanio rerio) dvr1 Polyclonal antibody
Uniprot No.
Target Names
dvr1
Alternative Names
dvr1 antibody; dvr-1 antibody; vg1 antibody; Protein DVR-1 antibody
Raised in
Rabbit
Species Reactivity
Danio rerio (Zebrafish) (Brachydanio rerio)
Immunogen
Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) dvr1 protein
Immunogen Species
Danio rerio (Zebrafish) (Brachydanio rerio)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Serves to facilitate the differentiation of either mesoderm or endoderm either as a cofactor in an instructive signal or by providing permissive environment.
Gene References into Functions
  1. Together, these findings demonstrate that Gdf3 is an essential cofactor of Nodal signaling during establishment of the embryonic axis. PMID: 29140249
  2. Collectively, these data indicate that gdf3 is critical for robust Nodal signaling at multiple stages in zebrafish embryonic development. PMID: 29140250
  3. Dvr1 acts as a direct and essential mediator for convergence and extension cell movements during zebrafish gastrulation. PMID: 24892953
  4. Dvr1 is responsible for enabling the transfer of a left-right signal from Kupffer's vesicle to lateral plate mesoderm. PMID: 23791819
  5. serum Vg in zebrafish D. rerio is an acute phase protein with bacterial-binding and inhibiting activities. PMID: 20006406
  6. Vg1 signaling in zebrafish depends on EGF-CFC proteins, but not on Nodal signals. Vg1 binds to and signal through Activin receptors only in the presence of EGF-CFC proteins. PMID: 12514096

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Subcellular Location
Secreted.
Protein Families
TGF-beta family
Tissue Specificity
Abundant in ovaries and eggs, and equally distributed among all blastomeres.
Database Links

KEGG: dre:30125

STRING: 7955.ENSDARP00000055378

UniGene: Dr.307

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