Recombinant Danio rerio Protein DVR-1 (dvr1)

Code CSB-EP330463DIL
Abbreviation Recombinant Zebrafish dvr1 protein
MSDS
Size $388
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  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Product Details

Purity
Greater than 90% as determined by SDS-PAGE.
Activity
Not Test
Target Names
dvr1
Uniprot No.
Research Area
Others
Alternative Names
dvr-1, vg1
Species
Danio rerio (Zebrafish) (Brachydanio rerio)
Source
E.coli
Expression Region
241-355aa
Target Protein Sequence
SASYYLPVTPSNVCKPRRLYIDFKDVGWQDWIIAPQGYLANYCHGECPFPLSESLNGTNHAILQTLVHSFDPKGTPQPCCVPIKLSPISMLYYDNNDNVVLRHYEDMVVDECGCR
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Mol. Weight
20.0 kDa
Protein Length
Full Length of Mature Protein
Tag Info
C-terminal 6xHis-tagged
Form
Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA
Please contact us to get it.

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Target Background

Function
Serves to facilitate the differentiation of either mesoderm or endoderm either as a cofactor in an instructive signal or by providing permissive environment.
Gene References into Functions
  1. Together, these findings demonstrate that Gdf3 is an essential cofactor of Nodal signaling during establishment of the embryonic axis. PMID: 29140249
  2. Collectively, these data indicate that gdf3 is critical for robust Nodal signaling at multiple stages in zebrafish embryonic development. PMID: 29140250
  3. Dvr1 acts as a direct and essential mediator for convergence and extension cell movements during zebrafish gastrulation. PMID: 24892953
  4. Dvr1 is responsible for enabling the transfer of a left-right signal from Kupffer's vesicle to lateral plate mesoderm. PMID: 23791819
  5. serum Vg in zebrafish D. rerio is an acute phase protein with bacterial-binding and inhibiting activities. PMID: 20006406
  6. Vg1 signaling in zebrafish depends on EGF-CFC proteins, but not on Nodal signals. Vg1 binds to and signal through Activin receptors only in the presence of EGF-CFC proteins. PMID: 12514096

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Subcellular Location
Secreted.
Protein Families
TGF-beta family
Tissue Specificity
Abundant in ovaries and eggs, and equally distributed among all blastomeres.
Database Links

KEGG: dre:30125

STRING: 7955.ENSDARP00000055378

UniGene: Dr.307

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