dyn-1 Antibody

Datasheet

Code	CSB-PA340049XA01CXY
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Product Details

Full Product Name

Rabbit anti-Caenorhabditis elegans dyn-1 Polyclonal antibody

Uniprot No.

P39055

Target Names

dyn-1

Alternative Names

dyn-1 antibody; C02C6.1 antibody; Dynamin antibody; EC 3.6.5.5 antibody

Raised in

Rabbit

Species Reactivity

Caenorhabditis elegans

Immunogen

Recombinant Caenorhabditis elegans dyn-1 protein

Immunogen Species

Caenorhabditis elegans

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis. Required for coelomocyte endocytosis. Involved in apoptotic cell phagocytosis. Required for recruitment of phosphatidylinositol 3-kinase piki-1 to phagosomes. May play a role in rab-5 recruitment to cell-corpses-containing phagosomes but not to endosomes. Required for embryonic and larval development.

Gene References into Functions

dynamin is a molecular motor which would be involved in GLUT4 translocation by facilitating exocytosis PMID: 28853753
Results describe the oligomerization of dynamin-1 (DYN-1) in living C. elegans embryos and identified DYN-1 mutations that abolish DYN-1's oligomerization or GTPase activities. PMID: 20016007
In Caenorhabditis elegans, dynamin localized to newly formed cleavage furrow membranes and accumulated at the midbody of dividing embryos in a manner similar to dynamin localization in mammalian cells PMID: 12498685
The Caenorhabditis elegans dynamin ortholog, DYN-1, maintains anterior polarity cues. PMID: 19531359

Subcellular Location

Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasmic vesicle, phagosome membrane; Peripheral membrane protein.

Protein Families

TRAFAC class dynamin-like GTPase superfamily, Dynamin/Fzo/YdjA family

Tissue Specificity

Expressed in motor neurons in the head and in ventral nerve cord and, to a lesser extent, in sensory neurons in the nerve ring and the tail and interneurons. Expressed in pharyngeal-intestinal valve, intestinal-rectal valve and in intestinal cells.

Database Links

KEGG: cel:CELE_C02C6.1

STRING: 6239.C02C6.1b

UniGene: Cel.19561

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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dyn-1 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background