Defa1 Antibody

Code CSB-PA006652ZA01MO
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Product Details

Full Product Name
Rabbit anti-Mus musculus (Mouse) Defa1 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
Defa1 antibody; Defcr antibody; Defcr1Alpha-defensin 1 antibody; Cryptdin-1 antibody; Defensin-related cryptdin peptide antibody
Raised in
Species Reactivity
Mus musculus
Recombinant Mus musculus Defa1 protein
Immunogen Species
Mus musculus (Mouse)
Purification Method
Protein A/G
It differs from different batches. Please contact us to confirm it.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Tested Applications
ELISA, WB (ensure identification of antigen)
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

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Target Background

Probably contributes to the antimicrobial barrier function of the small bowel mucosa. Has antibacterial activity against attenuated mutants of S.typhimurium.
Gene References into Functions
  1. Mouse adenovirus 2 infection was enhanced by enteric alpha-defensins. PMID: 28622386
  2. Decreased alpha-defensin is associated with intestinal inflammation in a model of inflammatory bowel disease. PMID: 20222124
  3. cryptdin-1 and cryptdin-4 exhibit circadian oscillation PMID: 16129697
  4. the Arg5-Glu13 salt bridge in alpha-defensin is conserved for defensin in vivo stability PMID: 16246847
  5. MMP-7 activates mouse paneth cell pro-alpha-defensins PMID: 16822871

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Subcellular Location
Protein Families
Alpha-defensin family
Tissue Specificity
Paneth cells of the small bowel.
Database Links

KEGG: mmu:13216

UniGene: Mm.425522

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