ea Antibody

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Code	CSB-PA321130XA01DLU
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Target Background

Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) ea Polyclonal antibody

Uniprot No.

P13582

Target Names

Alternative Names

ea antibody; CG4920Serine protease easter antibody; EC 3.4.21.- antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) ea protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

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Target Background

Function

Component of the extracellular signaling pathway that establishes the dorsal-ventral pathway of the embryo. Three proteases; ndl, gd and snk process easter to create active easter. Active easter defines cell identities along the dorsal-ventral continuum by activating the spz ligand for the Tl receptor in the ventral region of the embryo.

Gene References into Functions

The study reports the expression and refolding of Easter, and show that the renatured enzyme performs the activation cleavage of two spatzle isoforms. PMID: 23729565
Easter plays a role in generating the wild-type shape of the Dorsal gradient in the developing Drosophila embryo PMID: 12421704

Subcellular Location

Secreted.

Protein Families

Peptidase S1 family, CLIP subfamily

Database Links

KEGG: dme:Dmel_CG4920

STRING: 7227.FBpp0082539

UniGene: Dm.2421

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