efnb2a Antibody

1. Notch1 activation induces expression of ephrin b2a (efnb2a) and neuregulin 1 (nrg1) in the endocardium to promote trabeculation and forced Notch activation in the absence of cardiac contraction rescues efnb2a and nrg1 expression PMID: 26628092
2. We identified ephrinB2a as a target of hif1 pathway activation, showed that knock-down of ephrinB2a rescued the guidance errors, and showed that the receptor ephA4a is expressed in a pattern complementary to the misrouting axons PMID: 22511881
3. Somite expression of known vascular guidance cues, efnb2, sema3a2, and plexinD1 are disrupted, suggesting that the inter-somitic vessel vascular phenotype is due to disruption of these cues. PMID: 21038448
4. The ephrinB2a may signal a subpopulation of RGC axons that they have reached their target neurons in the tectum. PMID: 15007827
5. EphrinB2a is critically involved in increasing the probability of neurons projecting to rhombomere 2 through a reverse signaling mechanism. PMID: 17507550
6. Data show that EfnB2a is required in developing hindbrain for normal cell affinity and that EphA4 and EfnB2a regulate cell affinity independently within their respective rhombomeres. PMID: 19135438
7. first embryonic vein formed by selective sprouting of progenitor cells from precursor vessel, followed by vessel segregation; these processes were regulated by EphrinB2 & EphB4 which are expressed in arterial-fated & venous-fated progenitors respectively PMID: 19815777

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KEGG: dre:30219

STRING: 7955.ENSDARP00000010432

UniGene: Dr.75819