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env Antibody

Datasheet
Code CSB-PA320630XA01BAB
Size US$299
Image
  • Western Blot
    Positive WB detected in: recombinant protein
    All lanes:env Antibody at 1:1000
    Secondary
    Goat polyclonal to rabbit IgG at 1/20000 dilution
    Predicted band size: 59.9 kDa
    Observed band size: 60 kDa
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Product Details

Full Product Name
Rabbit anti-Baboon endogenous virus (strain M7) env Polyclonal antibody
Uniprot No.
P10269
Target Names
env
Alternative Names
Envelope glycoprotein (Env polyprotein) [Cleaved into: Surface protein (SU) (Glycoprotein 70) (gp70); Transmembrane protein (TM) (Glycoprotein p20E); R-peptide (p2E)] env
Raised in
Rabbit
Species Reactivity
Baboon endogenous virus (strain M7)
Immunogen
Recombinant Baboon endogenous virus (strain M7) env protein (19-503aa)
Immunogen Species
Baboon endogenous virus (strain M7)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
Protocols
ELISA Protocol
Western Blotting(WB) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
The surface protein (SU) attaches the virus to the host cell by binding to its receptor. This interaction triggers the refolding of the transmembrane protein (TM) and is thought to activate its fusogenic potential by unmasking its fusion peptide. Fusion occurs at the host cell plasma membrane.; The transmembrane protein (TM) acts as a class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes. Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm.
Subcellular Location
[Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein.; [Surface protein]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein.; [R-peptide]: Host cell membrane; Peripheral membrane protein.
Database Links

KEGG: vg:22318530

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