mks-5 Antibody

Datasheet

Code	CSB-PA600629XA01CXY
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Product Details

Full Product Name

Rabbit anti-Caenorhabditis elegans mks-5 Polyclonal antibody

Uniprot No.

Q09459

Target Names

mks-5

Alternative Names

mks-5 antibody; ftm antibody; nphp-8 antibody; C09G5.8Protein fantom antibody; Meckel syndrome protein homolog antibody

Raised in

Rabbit

Species Reactivity

Caenorhabditis elegans

Immunogen

Recombinant Caenorhabditis elegans mks-5 protein

Immunogen Species

Caenorhabditis elegans

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Thought to have an important role in cilia formation and cilia-mediated chemosensation. Involved in the docking of other MKS/MKSR proteins localized to the transition zone of the cilia.

Gene References into Functions

findings expand the repertoire of MKS module-associated proteins and suggest an MKS-5 and CEP-290-dependent assembly pathway for building a functional ciliary transition zone PMID: 26982032
MKS-5 acts to exclude membrane-associated signalling proteins from the transition zone and limits PIP2 ciliary abundance, creating an optimal, discrete ciliary signalling compartment. PMID: 26392567
these data suggest that NPHP-8/RPGRIP1L plays an important role in cilia formation and cilia-mediated chemosensation in a cell type-specific manner. PMID: 21689635

Subcellular Location

Cell projection, cilium. Note=Localizes to the transition zone.

Protein Families

RPGRIP1 family

Tissue Specificity

Expressed at the transition zone at the base of cilia. Expressed in ciliated sensory neurons, including the amphid neurons in the head.

Database Links

KEGG: cel:CELE_C09G5.8

STRING: 6239.C09G5.8a

UniGene: Cel.15908

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Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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mks-5 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background