foxd3-a Antibody

Code CSB-PA866767XA01XBE
Size Enquire
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Xenopus laevis (African clawed frog) foxd3-a Polyclonal antibody
Uniprot No.
Target Names
foxd3-a
Alternative Names
foxd3-a antibody; fkh6 antibody; foxd3aForkhead box protein D3-A antibody; FoxD3-A antibody; FoxD3a antibody; Fork head domain-related protein 6 antibody; FKH-6 antibody; Forkhead protein 6 antibody; xFD-6 antibody; xFKH6 antibody
Raised in
Rabbit
Species Reactivity
Xenopus laevis (African clawed frog)
Immunogen
Recombinant Xenopus laevis (African clawed frog) foxd3-a protein
Immunogen Species
Xenopus laevis (African clawed frog)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Transcriptional repressor that is an essential upstream regulator of neural crest determination and mesoderm induction. Functions by recruiting the transcriptional corepressor tle4. Also acts in a negative auto-regulator loop by inhibiting the transcription of its own gene.
Gene References into Functions
  1. results indicate that tcf1 acts as an essential activator of foxd3, which is critical for dorsal mesoderm formation in early embryos PMID: 23585352
  2. findings show that FoxD3 is required for Nodal expression in the Spemann organizer and this function is essential for dorsal mesoderm formation PMID: 17092955
  3. FoxD3 recruitment of Groucho corepressors is essential for the transcriptional repression of target genes and induction of mesoderm in Xenopus PMID: 17138566
Subcellular Location
Nucleus.
Tissue Specificity
Initially located within the dorsal blastopore lip (Spemann organizer) at the mid-gastrula stage. As expression fades in the neuroectoderm, expression begins in the head mesoderm in two regions at the lateral borders of the presumptive neural plate. These
Database Links

KEGG: xla:373548

UniGene: Xl.525

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1