glp-1 Antibody

1. These results provide the first experimental evidence of an essential role for HSP90 in Notch signaling in development. PMID: 29507057
2. The authors find that Notch-dependent active transcription sites occur in a probabilistic fashion and, unexpectedly, do so in a steep gradient across the stem cell pool. PMID: 27705743
3. Zygotically expressed MOM-2 (Wnt) is responsible for two distinct cell-cell interactions as the MS blastomere produces one-third of the body wall muscles. Both the inhibitory and the activating interactions require precise spatiotemporal expression of zygotic MOM-2, which is dependent upon two distinct GLP-1 Notch signals. PMID: 28049659
4. Study suggests that GLP-1 signaling is directly responsible for driving all stages of proliferation in the wild-type germline, and loss of its activity causes differentiation without intervening, distinctly regulated transit-amplifying divisions. PMID: 26158953
5. glp-1(ar202), a temperature-sensitive gain-of-function C. elegans NOTCH mutant, was employed to delineate NOTCH-driven tumor responses to radiotherapy. PMID: 26120834
6. regulatory element is highly conserved in the paralogous glp-1 genomic environment, suggesting redundant developmental and physiological roles for the two Notch paralogs in the C. elegans nervous system. PMID: 23305862
7. POS-1 regulates glp-1 mRNA translation by blocking access of other RNA-binding proteins to a key regulatory sequence PMID: 23034181
8. The functional defect in glp-1(Pro) mutants occurs prior to or at the level of ligand interaction. PMID: 12586701
9. the balance between POS-1 and SPN-4 controls the translation of maternal glp-1 mRNA PMID: 12702662
10. Results suggest that TBX-37 and TBX-38 play a key role in distinguishing the outcomes of two sequential Glp-1/Notch-mediated interactions. PMID: 15056620
11. Data support a model in which GLP-1 function in MSP-dependent oocyte growth is separable from its role in the proliferation versus meiotic entry decision. PMID: 19502484

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KEGG: cel:CELE_F02A9.6

STRING: 6239.F02A9.6

UniGene: Cel.6196