GLR3.4 Antibody

Code CSB-PA812752XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) GLR3.4 Polyclonal antibody
Uniprot No.
Target Names
GLR3.4
Alternative Names
GLR3.4 antibody; GLR4 antibody; GLUR3 antibody; At1g05200 antibody; YUP8H12.19Glutamate receptor 3.4 antibody; AtGLR4 antibody; Ligand-gated ion channel 3.4 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana GLR3.4 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Glutamate-gated receptor that probably acts as non-selective cation channel, at least in hypocotyls (Probable). Can be triggered by Asn, Ser, Gly and, to a lower extent, Ala, Cys and Glu. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells (Probable). Plays an important role in the calcium-based fast transmission of environmental stress. Acts as negative regulator of lateral root initiation and development. May restrict primordia numbers and position along the root axis by a signaling process originating in the phloem. AtGLR3.4-mediated cytosolic calcium influx may be involved in the regulation of seed germination under salt stress by modulating sodium accumulation through the SOS pathway.
Gene References into Functions
  1. AtGLR3.4-mediated Ca2+ influx may be involved in the regulation of seed germination under salt stress. PMID: 29432559
  2. AtGLR3.4 in particular and GLRs in general could play an important role in the Ca(2+) -based, fast transmission of environmental stress. PMID: 15864638
  3. The effect of 6 amino acids on the glutamate receptors of A. thaliana, and the role of GLR3.3 and GLR3.4 in the channel mechanisms are reported. PMID: 18162597
Subcellular Location
Cell membrane; Multi-pass membrane protein. Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein Families
Glutamate-gated ion channel (TC 1.A.10.1) family
Tissue Specificity
Highly expressed in roots and at lower levels in leaves and siliques. Expressed in seedlings, cotyledons, roots (e.g. root hairs, epidermis and cortex cells), stems, leaves (e.g. vascular bundles and hydathodes), and siliques. Expressed in root phloem.
Database Links

KEGG: ath:AT1G05200

STRING: 3702.AT1G05200.1

UniGene: At.10412

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