GLUL Antibody

Code CSB-PA009553ZA01DXU
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Product Details

Full Product Name
Rabbit anti-Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) GLUL Polyclonal antibody
Uniprot No.
Target Names
GLUL
Alternative Names
GLULGlutamine synthetase antibody; GS antibody; EC 6.3.1.2 antibody; Glutamate--ammonia ligase antibody; Palmitoyltransferase GLUL antibody; EC 2.3.1.225 antibody
Raised in
Rabbit
Species Reactivity
Cricetulus griseus
Immunogen
Recombinant Cricetulus griseus GLUL protein
Immunogen Species
Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

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Target Background

Function
Glutamine synthetase that catalyzes the ATP-dependent conversion of glutamate and ammonia to glutamine. Its role depends on tissue localization: in the brain, it regulates the levels of toxic ammonia and converts neurotoxic glutamate to harmless glutamine, whereas in the liver, it is one of the enzymes responsible for the removal of ammonia. Essential for proliferation of fetal skin fibroblasts. Independently of its glutamine synthetase activity, required for endothelial cell migration during vascular development: acts by regulating membrane localization and activation of the GTPase RHOJ, possibly by promoting RHOJ palmitoylation. May act as a palmitoyltransferase for RHOJ: able to autopalmitoylate and then transfer the palmitoyl group to RHOJ. Plays a role in ribosomal 40S subunit biogenesis.
Subcellular Location
Cytoplasm, cytosol. Microsome. Mitochondrion. Cell membrane; Lipid-anchor.
Protein Families
Glutamine synthetase family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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