2S seed storage albumin Antibody

Code CSB-PA324829ZA01GGV
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Product Details

Full Product Name Rabbit anti-Glycine max (Soybean) (Glycine hispida) GM2S-1 Polyclonal antibody
Uniprot No. P19594
Target Names GM2S-1
Alternative Names 2S albumin antibody; GM2S-1 antibody; Napin-type 2S albumin 3) [Cleaved into: 2S albumin small chain antibody; Aspartic acid-rich peptide antibody; Lunasin); 2S albumin large chain antibody; 8 kDa methionine-rich protein antibody; 8 kDa MRP)] antibody
Raised in Rabbit
Species Reactivity Glycine max
Immunogen Recombinant Glycine max 2S seed storage albumin protein
Immunogen Species Glycine max (Soybean) (Glycine hispida)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables ① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time Made-to-order (12-14 weeks)

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Target Background

Function
(From Uniprot)
This is a 2S seed storage protein.; binds to mammalian chromatin, preventing the normal formation of the kinetochore complex in the centromere and leading to the disruption of mitosis.
Gene References into Functions
  1. A potential strategy for recombinant production of bioactive lunasin in industry: production of anti-inflammatory agent by cloning a tandem repeat of Lunasin in Pichia pastoris. PMID: 29506820
  2. lunasin treatment could reverse the effects of ox-LDL on the expression of eNOS and PAI-1, the direct target genes of KLF2. Mechanistically, it was proven that the MEK5/ERK5 pathway mediates the effects of lunasin on KLF2 expression. PMID: 29096169
  3. lunasin will have promising potential as a novel nutritional supplement or drug candidate for RA due to its potency of suppressing synovial cell proliferation PMID: 25692134
Protein Families 2S seed storage albumins family
Tissue Specificity Expressed in cotyledons (Ref.2). Maximal expression in parenchyma cells undergoing DNA endoreduplication and cell expansion but not in actively dividing cells of the cotyledon.
Database Links

KEGG: gmx:548076

STRING: 3847.GLYMA13G36400.1

UniGene: Gma.32309

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