Tre1 Antibody

1. Bifurcation of the Tre1 G protein-coupled receptor signaling response via G protein-dependent and independent branches enables distinct spatiotemporal regulation of germ cell migration. PMID: 28687666
2. feminizing the Tre1-expressing neurons in male flies leads to rapid courtship initiation, a phenotype that leads to increased reproductive success; Tre1 is expressed in a sexually dimorphic pattern in olfactory sensory neurons and the central nervous system PMID: 26721856
3. role of the arginine of the NRY motif in Tre1 was investigated; results suggest that a salt bridge may form between this critical arginine and an aspartic acid in transmembrane alpha-helix (TM6)in Tre1 PMID: 24044607
4. The scattershot allele results in an in-frame deletion of 8 amino acids at the junction of the third transmembrane domain and the second intracellular loop of Tre1 that dramatically impairs the function of this GPCR in germ cell migration. PMID: 20676220
5. plays an important role in regulation of germ cell migration, polarity , cell adhesion, and cadherin binding. (review) PMID: 20058705
6. Tre1 is a G protein-coupled receptor that directs transepithelial migration of Drosophila germ cells PMID: 14691551
7. Down-regulation of E-cadherin causes germ cell dispersal but is not sufficient for transepithelial migration in the absence of Tre1, suggesting a new mechanism for Tre1 GPCR function that links cell polarity, modulation of cell adhesion, and invasion. PMID: 18824569

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KEGG: dme:Dmel_CG3171

STRING: 7227.FBpp0070813

UniGene: Dm.18422