hnf1ba Antibody

1. Data show that hnf1ba generates a permissive domain for Wnt signaling activity in the foregut endoderm PMID: 23720049
2. essential for normal segmentation of nephrons during kidney organogenesis PMID: 23160512
3. Knockdown of pk1a led to decreased expression of vhnf1, a homeodomain gene previously shown to be involved in biliary development and in kidney cyst formation; forced expression of vhnf1 mRNA led to rescue of the pk1a morphant phenotype PMID: 21215262
4. Data show that vhnf1 functions in two ways to subdivide the zebrafish caudal hindbrain domain (r4-r7) into individual rhombomeres. PMID: 12835397
5. Zebrafish tcf2 gene, composed of 9 exons, was mapped to linkage group LG15. PMID: 15302404
6. vhnf1 acts largely independently of val to repress the rhombomere 4 'hox code' posterior to the rhombomere 4-5 boundary PMID: 15342476
7. Vhnf1 expression within the posterior neural tube (up to r5) promotes posterior and dorsal fates in the otic vesicle, at the expense of anterior and ventral fates. PMID: 17137573
8. investigated the signaling pathways that regulate vhnf1 expression during pancreas development PMID: 17217944
9. Data show that zebrafish mutants for Tcf2 fail to specify a single lumen in their gut tube and instead develop multiple lumens, and show that Tcf2 controls single lumen formation by regulating claudin15 and Na+/K+-ATPase expression. PMID: 17632505
10. vHNF1 plays crucial role at the earliest steps of liver induction: the acquisition of endoderm competence and the hepatic specification. PMID: 18635606
11. It was concluded that hnf1b(hi2169) is hypomorphic to hnf1b(hi1843) and that, while hnf1b is required for r5/r6 gene expression in the hindbrain, r5/r6 gene expression can be experimentally induced independently of hnf1b anterior to the hindbrain. PMID: 18945197

Show More

Hide All

KEGG: dre:792391

STRING: 7955.ENSDARP00000011119

UniGene: Dr.118179