Hr38 Antibody

1. Hr38 was identified as a novel immediate early gene that is transiently expressed in the male silkmoth Bombyx mori by female odor stimulation. Hr38 was also used as a neural activity marker in the fly Drosophila melanogaster. PMID: 24120640
2. DHR38 might modulate the activity of the Usp-EcR heterodimer by forming complexes with both of its components PMID: 22628309
3. dHR38-N-Terminal domain exhibits a characteristic reminiscent of pre-molten globule-like intrinsically disordered proteins PMID: 21064127
4. Nutritional regulation of DHR38 expression maintains the proper uptake and storage of glycogen during the growing larval stage of development. PMID: 21084378
5. A second ecdysteroid signaling pathway is mediated by DHR38. DHR38 also heterodimerizes with Ultraspiralcle, and this complex responds to a distinct class of ecdysteroids in a manner that is independent of the ecdysteroid receptor. PMID: 12809604
6. Hr38 is a nuclear receptor which can assume an active conformation in the absence of a ligand agonist. PMID: 12852843
7. Gain and loss of function studies also implicate DHR38, the Drosophila homolog of vertebrate NGFI-B-type nuclear receptors, as an important activator of the ACP65A gene. PMID: 16106360
8. DHR38 may act as a positive regulator of neural Ddc expression PMID: 18059550
9. DHR38(Y214) mutants display minor effects on ecdysone-regulated transcription at the onset of metamorphosis PMID: 19235727

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KEGG: dme:Dmel_CG1864

STRING: 7227.FBpp0080927

UniGene: Dm.2701