HRR25 Antibody

1. The C-terminal region of Hrr25 is required for normal inhibition of expression of Haa1 target genes TPO2 and YRO2 and is important for cell growth but is not required for cell morphogenesis PMID: 28432100
2. Together, the Hrr25 central domain and Mam1 form a novel, contiguous embellishment to the Hrr25 kinase domain that affects Hrr25 conformational dynamics and enzyme kinetics. PMID: 27491543
3. Hrr25, a homolog of CSNK1D/casein kinase 1delta, regulates 3 of 4 selective autophagy-related pathways in the budding yeast Saccharomyces cerevisiae by a uniform mechanism: phosphoregulation of the receptor-scaffold interaction PMID: 25700828
4. Hrr25 protein kinase directly modifies Elp1 on two sites and we provide evidence that phosphorylation plays a positive role in the tRNA modification PMID: 25569479
5. Hrr25 is essential for ribosome assembly in Saccharomyces cerevisiae. PMID: 25778921
6. Hrr25 is responsible for the phosphorylation of two receptor proteins: Atg19, which recognizes the assembly of vacuolar enzymes in the cytoplasm-to-vacuole targeting pathway, and Atg36, which recognizes superfluous peroxisomes in pexophagy. PMID: 25287303
7. the kinase activity of Hrr25 regulates the maturation of 40S ribosomal subunits PMID: 16738661
8. We show that monopolin subunit Mam1 binds tightly to Hrr25, a highly conserved casein kinase 1 delta/varepsilon, and recruits it to meiosis I centromeres. Hrr25 kinase activity and Mam1 binding are both essential for monopolar attachment. PMID: 16990132
9. NUP53 is a target of HRR25. PMID: 17461799
10. Hrr25p-mediated phosphorylation of Tif6p plays a critical role in the biogenesis of 60 S ribosomal subunits in yeast cells. PMID: 18256024

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KEGG: sce:YPL204W

STRING: 4932.YPL204W