SSC1 Antibody

^{Rare Species}

Datasheet

Code	CSB-PA206965XA01SVG
Size	US$299
Image	Western Blot Positive WB detected in Recombinant protein All lanes: SSC1 antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 35.4 kDa Observed band size: 40 kDa
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

P0CS90

Target Names

SSC1

Alternative Names

Heat shock protein SSC1, mitochondrial (Endonuclease SceI 75 kDa subunit) (Endo.SceI 75 kDa subunit) (mtHSP70) SSC1 ENS1 YJR045C J1639

Species Reactivity

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Immunogen

Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) SSC1 protein (363-654aa)

Immunogen Species

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Protein G

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Description

The SSC1 polyclonal antibody is produced by immunizing a rabbit with a recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) SSC1 protein (363-654aa) to elicit an antibody response. The serum is collected from the rabbit to obtain polyclonal antibodies, which subsequently undergo protein G affinity chromatography purification. The efficacy of the SSC1 antibody in detecting Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) SSC1 protein is validated through ELISA and WB assays.

The Saccharomyces cerevisiae SSC1 protein acts as a molecular chaperone that assists in protein folding, assembly, and transport within the cell. The SSC1 protein helps prevent protein misfolding and aggregation, ensuring proper protein function and maintaining cellular homeostasis. Additionally, it plays a role in the response to stress conditions, such as heat shock, by aiding in the refolding of denatured proteins.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Constitutes the ATP-driven core of the motor and binds the precursor preprotein. Required for the import of the processed frataxin homolog YFH1 into the mitochondrion.

Gene References into Functions

Amino acid substitution within SSC1 reveals structural elements within mtHsp70s that are required for allosteric modulation of the chaperone cycle. PMID: 24829379
Results show that mtHsp70-Cox4 complex likely serves as a novel delivery system to channel Cox4 into the assembly line when needed. PMID: 23864706
The intrinsic dynamics of the substrate-binding domain of Ssc1 was observed to be uncoupled from the dynamic interactions between substrate- and nucleotide-binding domains. PMID: 23624933
the critical amino acid sequence of Ssc1 and Ssc3 that can "make or break" mtHsp70 chaperone function. PMID: 21474445
interactions between Tim44 and mtHsp70, controlled by polypeptide binding, are required for efficient translocation across the mitochondrial inner membrane PMID: 15489862
The N-terminal 167-amino-acid segment of mature Tim44 is sufficient for both interaction with mtHsp70 and destabilization of a Tim44-mtHsp70 complex caused by client protein binding. PMID: 18426906

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Subcellular Location

Mitochondrion matrix.

Protein Families

Heat shock protein 70 family

Database Links

KEGG: sce:YJR045C

STRING: 4932.YJR045C

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Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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