ICMTA Antibody

Datasheet

Code	CSB-PA866990XA01DOA
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Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) ICMTA Polyclonal antibody

Uniprot No.

Q9FMW9

Target Names

ICMTA

Alternative Names

ICMTA; PCM; STE14; STE14A; At5g23320; MKD15.18; Protein-S-isoprenylcysteine O-methyltransferase A; AtICMTA; Isoprenylcysteine carboxylmethyltransferase A; Prenylated protein carboxyl methyltransferase A; Prenylcysteine carboxyl methyltransferase A; AtPCM

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana ICMTA protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues, resulting in the modulation of the function of prenylated proteins. Involved in negative regulation of abscisic acid signaling. Carboxyl methylation is a reversible and potentially regulated step in the post-translational modification of prenylated proteins.

Gene References into Functions

Observations support the hypothesis that the ABA hypersensitive phenotype of fcly plants is the result of FC accumulation and inhibition of ICMT. PMID: 19969520
phenotype of RNAi lines is similar to farnesyltransferase beta-subunit mutant enhanced response to abscisic acid2 but is more subtle PMID: 18641086

Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Protein Families

Class VI-like SAM-binding methyltransferase superfamily, Isoprenylcysteine carboxyl methyltransferase family

Tissue Specificity

Expressed primarily in flowers, stems, leaves and roots. Almost not expressed in siliques. Detected in root tips and vascular tissues of roots, cotyledons, petiols, hypocotyls, filaments, pollen grains and the distal and proximal portions of the gynoecium

Database Links

KEGG: ath:AT5G23320

STRING: 3702.AT5G23320.1

UniGene: At.54958

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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ICMTA Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background