IL11 Antibody

Code CSB-PA324092ZA01MOV
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Product Details

Full Product Name
Rabbit anti-Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) IL11 Polyclonal antibody
Uniprot No.
Target Names
IL11
Alternative Names
Interleukin-11 (IL-11), IL11
Raised in
Rabbit
Species Reactivity
Macaca fascicularis
Immunogen
Recombinant Macaca fascicularis IL11 protein
Immunogen Species
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Conjugate
Non-conjugate
Clonality
Polyclonal
Isotype
IgG
Purification Method
Protein A/G
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

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Target Background

Function
Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and IL11RA activates a signaling cascade that promotes cell proliferation. Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. The interaction with the membrane-bound IL11RA and IL6ST stimulates 'classic signaling', whereas the binding of IL11 and soluble IL11RA to IL6ST stimulates 'trans-signaling'.
Subcellular Location
Secreted.
Protein Families
IL-6 superfamily
Database Links

KEGG: mcf:102118349

UniGene: Mfa.5402

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