IPS1 Antibody

Code CSB-PA337218XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) IPS1 Polyclonal antibody
Uniprot No.
Target Names
IPS1
Alternative Names
IPS1 antibody; MIPS1 antibody; At4g39800 antibody; T19P19.190 antibody; Inositol-3-phosphate synthase isozyme 1 antibody; AtIPS1 antibody; MIP synthase 1 antibody; EC 5.5.1.4 antibody; Myo-inositol 1-phosphate synthase 1 antibody; AtMIPS 1 antibody; MI-1-P synthase 1 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana IPS1 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Catalyzes the majority of myo-inositol synthesis required for plant growth and development. Acts as a repressor of programmed cell death and protects plant cells against cell death under high light intensity or long days. Controls its own transcription by inhibiting ATXR6 activity. Reduces the deposition of inhibitory histone marks on its own promoter.
Gene References into Functions
  1. works with MIPS2 AND MIPS3 to impact the overall synthesis of myo-inositol and overall inositol homeostasis PMID: 29777485
  2. chlorophyll accumulation Is required for the onset of programmed cell death (PCD) in myoinositol phosphate synthase1 (mips1) mutant. PMID: 26747283
  3. MIPS1 binds directly to its promoter to stimulate its own expression by locally inhibiting the spreading of ATXR5/6-dependent heterochromatin marks coming from a transposable element. PMID: 23341037
  4. MIPS1 has a significant impact on myo-inositol levels that is critical for maintaining levels of ascorbic acid, phosphatidylinositol, and ceramides that regulate growth, development, and cell death. PMID: 20215587
  5. Though MIPS localizes to the cytosol primarily in the endosperm during seed development, myo-inositol-6-phosphate, the final product of inositol phosphate metabolism, was present mainly in the embryo. PMID: 18603618

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Subcellular Location
Cytoplasm. Nucleus.
Protein Families
Myo-inositol 1-phosphate synthase family
Tissue Specificity
Expressed in siliques, leaves, roots, seed endosperm, but not in embryos. Highest expression in leaves, but restricted to vascular tissue in older leaves.
Database Links

KEGG: ath:AT4G39800

STRING: 3702.AT4G39800.1

UniGene: At.24599

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