INO1 Antibody

1. Data suggest that a specific pool of phosphatidic acid, associated with lipid droplet formation in perinuclear ER, is responsible for initial rapid exit of Opi1p from nucleus to ER and is required for Ino1 expression in presence of choline; interaction between Opi1p and Scs2p in ER membrane facilitates transit of phosphatidic acid from ER to mitochondria. PMID: 28924045
2. Transcriptional memory of INO1 requires a remodeled form of the Set1/COMPASS methyltransferase lacking Spp1, which dimethylates histone H3 lysine 4 (H3K4me2). PMID: 27336723
3. analysis of how myo-inositol-3-phosphate synthase is regulated by phosphorylation PMID: 23902760
4. While the pattern of regulation of these two genes was similar, results showed that intermediate levels of inositol repressed INO1 and induced SNA3. PMID: 23174187
5. Data show that the introns have a direct role in enhancing transcription of INO1 and ASC1 because there was a marked increase in nascent transcripts from these genes in the presence of an intron. PMID: 22586116
6. Interaction of a DNA zip code with the nuclear pore complex promotes H2A.Z incorporation and INO1 transcriptional memory. PMID: 20932479
7. Induction of INO1 resulted in acetylation of both histones H3 and H4 at the INO1 promoter and sequences farther downstream in the coding region, suggesting a gene-wide acetylation in response to transcriptional activation. PMID: 20018175
8. Full transcriptional activation of INO1 and another GRS-containing gene requires GRS I (gene recruitment sequences) mediated targeting of the promoter to the nuclear periphery. PMID: 20098417
9. unfolded protein response pathway induction not correlated with elevated INO1 expression PMID: 15371354
10. the intranuclear localization of INO1 can profoundly influence its mechanism of activation PMID: 15455074
11. cells with down-regulated Sah1 activity major alterations in the expression of the INO1 gene as well as in the localization of Opi1, a negative regulatory factor of phospholipid synthesis PMID: 18591246

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KEGG: sce:YJL153C

STRING: 4932.YJL153C