JHD1 Antibody

Code CSB-PA336665XA01SVG
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Product Details

Full Product Name Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) JHD1 Polyclonal antibody
Uniprot No. P40034
Target Names JHD1
Alternative Names JHD1 antibody; YER051W antibody; JmjC domain-containing histone demethylation protein 1 antibody; EC antibody; Jumonji/ARID domain-containing protein 1 antibody; ScJHDM1 antibody; [Histone-H3]-lysine-36 demethylase 1 antibody
Raised in Rabbit
Species Reactivity Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) JHD1 protein
Immunogen Species Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables ① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time Made-to-order (14-16 weeks)

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Target Background

(From Uniprot)
Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Does not demethylate H3 'Lys-4' nor 'Lys-79'.
Gene References into Functions
  1. These studies establish Jhd1 as a histone demethylase in budding yeast and suggest that Jhd1 functions to maintain the fidelity of histone methylation patterns along transcription units. PMID: 17470555
  2. Jhd1 and Rph1 demethylate histone H3 Lys36 in transcribed regions to promote elongation PMID: 17525156
  3. Possible role for jhd1 enzyme, through inhibition by succinate in paraganglioma oncogenesis. PMID: 17884808
Subcellular Location Nucleus.
Protein Families JHDM1 histone demethylase family
Database Links

KEGG: sce:YER051W

STRING: 4932.YER051W

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